In 1971, John List disappears after murdering his mother, wife and three children; he eludes the law for years until an age-scaled sculpture of the suspect and a true-crime TV program helps lead to his arrest in 1989.
An 11-year-old boy comes down with a fever and diarrhea after eating an undercooked burger; when his condition worsens, his mother drives him to a hospital and doctors discover E. coli destroying his body.
When an English couple go missing, police suspect their son killed them and must rely on mud and blood samples found in the couple's two cars to find their bodies.
When a woman goes missing from her home, police focus on her husband when an airline luggage tag and luminol point to an affair and murder; footage from a TV crew and Coast Guard photographs lead investigators to the suspect's missing boat.
When a woman exhibits strange flu-like symptoms before dying, investigators discover someone added thallium to her soda; detectives initially suspect her husband, but the case takes a sinister turn.
For ten years, the disappearance of a college co-ed remained a mystery; new scientific testing cast a different light on a man who had been a suspect all along.
The body of an insurance assessor is found in a river in Tampa, Fla.; a unique murder weapon and blatant clues lead the police straight to her careless killer.
When a high school athlete is killed in a hit-and-run accident, investigators hoped tiny paint chips and shards of plastic would lead them to the driver.
Handwriting and simple doodles complicate a car-bomb case and an alleged self-defense shooting in a peaceful British farming village as police uncover a husband's plot to kill his wife for insurance money.
A well-liked bank vice president collapses and dies after taking pain pills laced with cyanide; the search for a motive reveals a callous suspect who had murdered once before.
A man kills two people with bombs in an effort to get investors off his back, but authorities catch onto him, and he becomes sentenced to life with no chance of parole.
A man arrested for the sexual assault and attempted murder of a boy in a European country becomes linked to a murder in Zurich, Switzerland, through analysis of microorganisms.
Heavy rains and snow run-off carry manure into Milwaukee's water supply in 1993, leading to an epidemic of gastrointestinal illness affecting 400,000 people.
In a series of murders near Sacramento, Calif., a killer gags and molests prostitutes, cuts their clothes in random patterns and cuts off their hair; microscopic evidence helps solve the case.
Investigators reopen a case from 1984 involving the rape of a young Virginia woman when DNA testing refutes her identification of the rapist and calls everything into question, leading to the accused person's exoneration.
A speck of bicycle paint and a speck of nickel left over from a collision with a twice-convicted child molester's car provide critical clues in the murder of a 9-year-old.