Dr. Meegan Gruber specializes in performing surgery while patients are completely awake; Derrick orders lunch while getting his "man boobs" removed; Genny has a request to get rid of both of her chins; Megan needs surgery to fix her "ball sack arms."
Dr. Meegan Gruber faces the most daunting awake surgery of her career: removing a giant hanging stomach; Jason looks for a butt lift to help him scandalize all of Kentucky; a patient calls her psychic mid-surgery.
A pregnant Kayla is rushed to the ER for abdominal pain, but Dr. Crawford finds something; an entire bike brake is embedded in Jasmine's thigh; Mary has a fingernail stuck in her ear; Destiny's mouth smells like decaying flesh.
Doctor Crawford needs to remove a barbed nail embedded deeply in the forearm of a patient; Doctor Mellick must meticulously extract an unexpected item from an eye.
Chris tries to solve the 50-year-old mystery of why a woman was abandoned at a laundromat days after being born; a family enlists Lisa's help to track down the firstborn son that was placed for adoption, hoping to fulfill a father's dying wish.
The family's fight during Ed's surgery leaves Casey questioning whether he should go through with the surgery himself; Amy panics when she learns how difficult the Spartan Race will be; Amanda undergoes testing to see if her cancer has spread.
It's the moment of truth as Casey learns if he has been approved for life-saving surgery; Amanda has huge news regarding her cancer; Amy attempts a hellacious Spartan Race; the King family throws a party to reveal their shocking new looks.
A year after the Anderson family started their weight loss journey, they find that the honeymoon period is over as they begin to struggle; their 600-pound cousin Shavonne wants to follow in their footsteps.
Shavonne calls out the family for not losing weight; Naomi gets devastating news that might derail her goals for good; Drew attempts to re-enter the dating world for the first time in a decade; Chitoka tries to get back on track.
A 44-year-old mother of six has had at least 30 plastic surgery procedures to build the most extreme body in the world; she plans to go under the knife again to double her breast size to a shocking QQQ.
Winner of the Uganda's Ugliest Man contest, Godfrey has a rare disorder that has left him disfigured; with 10 children, a new baby on the way, and his condition worsening, he is seeking medical answers that will determine his future.
Milagros lives with tumors so heavy that her face droops down to her torso; after hiding away, a health scare is forcing her out into the world; twenty-one-year-old Lizzie is preparing to live independently even after tumors have grown over her eyes.
Summer has macromastia, a condition that causes her breasts to keep growing; with constant pain in her back and neck from breasts that are now a third of her overall body weight, Summer travels from Scotland to Los Angeles looking for answers.
In Brazil, Claudio lives with a condition that bent his head backward; ahead of his 50th birthday, he wants to climb a sacred mountain; in Norway, Birgitte lives with a different presentation of the same condition; she's training for the next Paralympics.
Riah has been addicted to baby wipes since she was 15 and goes through 500 a day, using them instead of showering; Brea has been addicted to eating sand for the past five years.
Danielle has been addicted to vapor rub for more than 20 years, going through more than 30 jars, inhalers and patches every week; 19-year-old Allison has been eating tires for the past six years, consuming 14 pounds every month.