A pirate throws a party that causes a situation below deck; a couple gets in a tangle that leaves one of them tied up for the night; a woman could be permanently blind if her eyes aren't treated.
Tommy wants to lose weight so he can marry his fiancée and have the life he always dreamed of with her, but to break the cycle of pathological eating that left him nearly bed-bound, he'll have to face a piece of his past he has always kept secret.
Twenty years after her father died as the result of a botched weight-loss surgery, Carrie is on the brink of eating herself to death; she must face the fear and grief of losing her father and end a cycle of toxic behavior with her husband, Chris.
Thederick has become housebound from eating and only goes outside to greet the ice cream man; after a recent hospital scare, it's finally clicked that if Dr. Now's program doesn't work for him, then nothing will.
Cindy is resistant to change and spends years creating a world that makes her feel safe; when her friend notices Cindy's health declining rapidly due to her size, she pushes Cindy to move to Houston and see Dr. Now.
Melissa has isolated herself at home and lost many friends to avoid feeling the shame of what her food addiction has done to her body; now, the only way to get her life back is to leave it behind to start a new one with Dr. Now's help in Houston.
Kenae is already big before her weight gain takes off after the death of her beloved mother; refusing to deal with the pain, Kenae turns to food to fill the void.
Mark sets out with a goal for weight-loss surgery, but as weight loss gets easier, he turns down medical advice and decides to do it on his own; Mark thinks he can lose 500 pounds by himself, but Dr. Now sees this as another excuse not to change.
With her weight spiraling, Stephanie needs her mom's help to care for her three kids; she's at the point where she'll have to lose weight or risk not having the chance to see her kids grow up.